Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). [electronic resource]
Producer: 20040624Description: 769-78 p. digitalISSN:- 1470-8728
- Acetyltransferases -- biosynthesis
- Adenoviridae -- genetics
- Aminoimidazole Carboxamide -- analogs & derivatives
- Animals
- Apoptosis
- CCAAT-Enhancer-Binding Proteins -- genetics
- Cells, Cultured
- DNA-Binding Proteins -- genetics
- Fatty Acid Synthases -- biosynthesis
- Gene Expression -- drug effects
- Genetic Vectors
- Glucose -- antagonists & inhibitors
- Insulin -- metabolism
- Islets of Langerhans -- cytology
- Lipids -- biosynthesis
- Male
- Rats
- Rats, Wistar
- Ribonucleotides -- pharmacology
- Sterol Regulatory Element Binding Protein 1
- Transcription Factors
- Transduction, Genetic
- Triglycerides -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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