Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR).

Diraison, Frédérique

Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). [electronic resource] - The Biochemical journal Mar 2004 - 769-78 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1470-8728

10.1042/BJ20031277 doi


Acetyltransferases--biosynthesis
Adenoviridae--genetics
Aminoimidazole Carboxamide--analogs & derivatives
Animals
Apoptosis
CCAAT-Enhancer-Binding Proteins--genetics
Cells, Cultured
DNA-Binding Proteins--genetics
Fatty Acid Synthases--biosynthesis
Gene Expression--drug effects
Genetic Vectors
Glucose--antagonists & inhibitors
Insulin--metabolism
Islets of Langerhans--cytology
Lipids--biosynthesis
Male
Rats
Rats, Wistar
Ribonucleotides--pharmacology
Sterol Regulatory Element Binding Protein 1
Transcription Factors
Transduction, Genetic
Triglycerides--metabolism