Repression of mitogen-activated protein kinase (MAPK) phosphatase-1 by anthracyclines contributes to their antiapoptotic activation of p44/42-MAPK. [electronic resource]
Producer: 20040129Description: 861-9 p. digitalISSN:- 0022-3565
- Animals
- Anthracyclines -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- Breast Neoplasms -- enzymology
- Cell Line, Tumor
- Clone Cells
- Dual Specificity Phosphatase 1
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Epithelial Cells -- drug effects
- Female
- Fluorescent Antibody Technique
- Gene Silencing -- drug effects
- Humans
- Luciferases -- biosynthesis
- Mice
- Mice, Knockout
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- metabolism
- Phosphorylation
- Promoter Regions, Genetic -- drug effects
- Protein Phosphatase 1
- Protein Tyrosine Phosphatases -- antagonists & inhibitors
- RNA, Messenger -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- drug effects
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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