Influence of a peptide linker on biodistribution and metabolism of antibody-conjugated benzyl-EDTA. Comparison of enzymatic digestion in vitro and in vivo. [electronic resource]
Producer: 19921222Description: 424-9 p. digitalISSN:- 1043-1802
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal -- metabolism
- Cathepsin B -- metabolism
- Cathepsin D -- metabolism
- Chromatography, High Pressure Liquid
- Cross-Linking Reagents -- pharmacokinetics
- Edetic Acid -- analogs & derivatives
- Endopeptidases -- metabolism
- Imidoesters -- pharmacokinetics
- Immunotoxins -- metabolism
- Indium Radioisotopes
- Liver -- enzymology
- Mice
- Molecular Sequence Data
- Oligopeptides -- metabolism
- Structure-Activity Relationship
- Tissue Distribution
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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