Identification of C8-methylguanine in the hydrolysates of DNA from rats administered 1,2-dimethylhydrazine. Evidence for in vivo DNA alkylation by methyl radicals. [electronic resource]
Producer: 19921125Description: 21524-7 p. digitalISSN:- 0021-9258
- 1,2-Dimethylhydrazine
- Alkylation
- Animals
- Carcinogens -- toxicity
- Chromatography, High Pressure Liquid
- Chromatography, Ion Exchange
- Colon -- chemistry
- DNA -- chemistry
- Dimethylhydrazines -- toxicity
- Free Radicals
- Guanine -- analogs & derivatives
- Liver -- chemistry
- Male
- Rats
- Rats, Sprague-Dawley
- Rats, Wistar
- Spectrometry, Mass, Fast Atom Bombardment
- Spectrophotometry, Ultraviolet
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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