Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat. [electronic resource]
Producer: 20040709Description: 1078-89 p. digitalISSN:- 0893-228X
- Administration, Oral
- Animals
- CD4 Lymphocyte Count
- CD8-Positive T-Lymphocytes -- immunology
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Eruptions -- etiology
- Drug Evaluation, Preclinical -- methods
- Exanthema -- chemically induced
- Female
- Food
- Forecasting
- Hepatomegaly -- chemically induced
- Liver -- drug effects
- Macrophages -- immunology
- Male
- Mice
- Mice, Inbred Strains
- Nevirapine -- administration & dosage
- Rats
- Rats, Inbred Lew
- Rats, Sprague-Dawley
- Skin -- drug effects
- Spleen -- cytology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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