Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat.
Shenton, Jacintha M
Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat. [electronic resource] - Chemical research in toxicology Sep 2003 - 1078-89 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0893-228X
10.1021/tx034064+ doi
Administration, Oral
Animals
CD4 Lymphocyte Count
CD8-Positive T-Lymphocytes--immunology
Disease Models, Animal
Dose-Response Relationship, Drug
Drug Eruptions--etiology
Drug Evaluation, Preclinical--methods
Exanthema--chemically induced
Female
Food
Forecasting
Hepatomegaly--chemically induced
Liver--drug effects
Macrophages--immunology
Male
Mice
Mice, Inbred Strains
Nevirapine--administration & dosage
Rats
Rats, Inbred Lew
Rats, Sprague-Dawley
Skin--drug effects
Spleen--cytology
Time Factors
Characterization of a potential animal model of an idiosyncratic drug reaction: nevirapine-induced skin rash in the rat. [electronic resource] - Chemical research in toxicology Sep 2003 - 1078-89 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0893-228X
10.1021/tx034064+ doi
Administration, Oral
Animals
CD4 Lymphocyte Count
CD8-Positive T-Lymphocytes--immunology
Disease Models, Animal
Dose-Response Relationship, Drug
Drug Eruptions--etiology
Drug Evaluation, Preclinical--methods
Exanthema--chemically induced
Female
Food
Forecasting
Hepatomegaly--chemically induced
Liver--drug effects
Macrophages--immunology
Male
Mice
Mice, Inbred Strains
Nevirapine--administration & dosage
Rats
Rats, Inbred Lew
Rats, Sprague-Dawley
Skin--drug effects
Spleen--cytology
Time Factors