The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation. [electronic resource]
Producer: 20030926Description: 9482-90 p. digitalISSN:- 0006-2960
- Binding Sites
- Catalysis
- Chlorobenzoates -- chemistry
- Escherichia coli -- enzymology
- Hydrogen Bonding
- Hydrolases -- chemistry
- Hydrolysis
- Kinetics
- Ligands
- Models, Molecular
- Molecular Structure
- Mutagenesis, Site-Directed
- Mutation -- genetics
- Spectrophotometry, Ultraviolet
- Spectrum Analysis, Raman
- Structure-Activity Relationship
- Substrate Specificity
- Thermodynamics
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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