The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation.

Dong, Jian

The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation. [electronic resource] - Biochemistry Aug 2003 - 9482-90 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0006-2960

10.1021/bi0347656 doi


Binding Sites
Catalysis
Chlorobenzoates--chemistry
Escherichia coli--enzymology
Hydrogen Bonding
Hydrolases--chemistry
Hydrolysis
Kinetics
Ligands
Models, Molecular
Molecular Structure
Mutagenesis, Site-Directed
Mutation--genetics
Spectrophotometry, Ultraviolet
Spectrum Analysis, Raman
Structure-Activity Relationship
Substrate Specificity
Thermodynamics