Predictive value of comparative molecular field analysis modelling of naphthalene inhibition of human CYP2A6 and mouse CYP2A5 enzymes. [electronic resource]
Producer: 20040617Description: 449-55 p. digitalISSN:- 0887-2333
- Animals
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Cytochrome P-450 CYP2A6
- Cytochrome P450 Family 2
- Enzyme Inhibitors -- pharmacology
- Female
- Humans
- Hydroxylation
- Kinetics
- Male
- Mice
- Mice, Inbred DBA
- Microsomes, Liver -- drug effects
- Mixed Function Oxygenases -- antagonists & inhibitors
- Models, Biological
- NADP -- metabolism
- Naphthalenes -- pharmacology
- Oxidation-Reduction
- Predictive Value of Tests
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Publication Type: Comparative Study; Journal Article
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