Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines. [electronic resource]
Producer: 20030612Description: 2390-8 p. digitalISSN:- 0146-0404
- Antibiotics, Antineoplastic -- pharmacology
- Apoptosis -- drug effects
- Blotting, Western
- Butyrates -- pharmacology
- Caspase 3
- Caspases -- metabolism
- Cell Cycle Proteins -- genetics
- Cell Division -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclins -- genetics
- Depsipeptides
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Fas Ligand Protein
- Flow Cytometry
- Histone Deacetylase Inhibitors
- Humans
- Hydroxamic Acids -- pharmacology
- Melanoma -- genetics
- Membrane Glycoproteins -- genetics
- Peptides, Cyclic -- pharmacology
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- RNA, Messenger -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Cells, Cultured
- Tumor Suppressor Proteins -- genetics
- Uveal Neoplasms -- genetics
- bcl-2-Associated X Protein
- fas Receptor -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.