Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1. [electronic resource]
Producer: 20030910Description: 28462-9 p. digitalISSN:- 0021-9258
- Alanine
- Casein Kinase II
- Cell Cycle Proteins -- metabolism
- Cell Division
- Cyclin-Dependent Kinase Inhibitor p27
- Cysteine Endopeptidases -- metabolism
- Enzyme Inhibitors -- pharmacology
- G1 Phase
- Gene Expression
- Guanosine Triphosphate -- pharmacology
- HeLa Cells
- Humans
- I-kappa B Proteins -- metabolism
- Leupeptins -- pharmacology
- Multienzyme Complexes -- antagonists & inhibitors
- Mutagenesis, Site-Directed
- NF-KappaB Inhibitor alpha
- Phosphorylation
- Proteasome Endopeptidase Complex
- Protein Serine-Threonine Kinases -- metabolism
- RNA -- metabolism
- RNA-Binding Proteins -- chemistry
- S Phase
- Structure-Activity Relationship
- Threonine -- metabolism
- Transfection
- Tumor Suppressor Proteins -- metabolism
- Ubiquitin-Protein Ligases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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