Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding. [electronic resource]
Producer: 20030814Description: 25933-9 p. digitalISSN:- 0021-9258
- ADAM Proteins
- ADAM17 Protein
- Animals
- Biotinylation
- Blotting, Western
- CHO Cells
- Cell Line
- Cricetinae
- DNA, Complementary -- metabolism
- Endoplasmic Reticulum -- metabolism
- Enzyme Activation
- Glycoproteins -- chemistry
- HeLa Cells
- Humans
- Metalloendopeptidases -- metabolism
- Microscopy, Confocal
- Microscopy, Fluorescence
- Molecular Sequence Data
- Mutation
- Precipitin Tests
- Protein Structure, Tertiary
- Protein Transport
- Reverse Transcriptase Polymerase Chain Reaction
- Transfection
- Transforming Growth Factor alpha -- metabolism
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- metabolism
- Zinc -- metabolism
- alpha 1-Antitrypsin -- metabolism
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Publication Type: Journal Article
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