Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP. [electronic resource]
Producer: 20030513Description: 369-78 p. digitalISSN:- 0741-5400
- 5-Lipoxygenase-Activating Proteins
- Arachidonate 5-Lipoxygenase -- genetics
- Carrier Proteins -- antagonists & inhibitors
- Cell Communication -- drug effects
- Cell Survival -- drug effects
- Enzyme Inhibitors -- pharmacology
- Humans
- Immunohistochemistry
- Leukotriene D4 -- pharmacology
- Lipoxygenase Inhibitors
- Membrane Proteins -- antagonists & inhibitors
- Microglia -- cytology
- Monocytes -- cytology
- Neuroblastoma -- pathology
- Neurons -- cytology
- RNA, Messenger -- analysis
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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