Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP.
Klegeris, Andis
Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP. [electronic resource] - Journal of leukocyte biology Mar 2003 - 369-78 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0741-5400
10.1189/jlb.1002482 doi
5-Lipoxygenase-Activating Proteins
Arachidonate 5-Lipoxygenase--genetics
Carrier Proteins--antagonists & inhibitors
Cell Communication--drug effects
Cell Survival--drug effects
Enzyme Inhibitors--pharmacology
Humans
Immunohistochemistry
Leukotriene D4--pharmacology
Lipoxygenase Inhibitors
Membrane Proteins--antagonists & inhibitors
Microglia--cytology
Monocytes--cytology
Neuroblastoma--pathology
Neurons--cytology
RNA, Messenger--analysis
Tumor Cells, Cultured
Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP. [electronic resource] - Journal of leukocyte biology Mar 2003 - 369-78 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0741-5400
10.1189/jlb.1002482 doi
5-Lipoxygenase-Activating Proteins
Arachidonate 5-Lipoxygenase--genetics
Carrier Proteins--antagonists & inhibitors
Cell Communication--drug effects
Cell Survival--drug effects
Enzyme Inhibitors--pharmacology
Humans
Immunohistochemistry
Leukotriene D4--pharmacology
Lipoxygenase Inhibitors
Membrane Proteins--antagonists & inhibitors
Microglia--cytology
Monocytes--cytology
Neuroblastoma--pathology
Neurons--cytology
RNA, Messenger--analysis
Tumor Cells, Cultured