Dominant-negative suppression of HCN channels markedly reduces the native pacemaker current I(f) and undermines spontaneous beating of neonatal cardiomyocytes. [electronic resource]
Producer: 20030205Description: 485-9 p. digitalISSN:- 1524-4539
- Adenoviridae -- genetics
- Animals
- Animals, Newborn
- Biological Clocks
- CHO Cells
- Cricetinae
- Cyclic Nucleotide-Gated Cation Channels
- Electric Conductivity
- Genetic Vectors
- Heart -- physiology
- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
- Ion Channels -- antagonists & inhibitors
- Muscle Proteins -- antagonists & inhibitors
- Mutation
- Myocardial Contraction
- Patch-Clamp Techniques
- Potassium Channels
- Rats
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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