Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamine. [electronic resource]
Producer: 20030204Description: 169-82 p. digitalISSN:- 0022-2623
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cell Division -- drug effects
- Cell Hypoxia -- drug effects
- Cyclic N-Oxides -- chemical synthesis
- Drug Screening Assays, Antitumor
- Humans
- Inhibitory Concentration 50
- Mice
- Oxidation-Reduction
- Solubility
- Structure-Activity Relationship
- Tirapazamine
- Triazines -- chemical synthesis
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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