Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways. [electronic resource]
Producer: 20030113Description: 695-706 p. digitalISSN:- 1535-7163
- Antibodies, Monoclonal -- pharmacology
- Antibodies, Monoclonal, Humanized
- Antineoplastic Agents -- pharmacology
- Blotting, Western
- Breast Neoplasms -- drug therapy
- Cell Cycle
- Cell Division -- drug effects
- Cell Separation
- Chromones -- pharmacology
- Cyclin D1 -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- pharmacology
- Flavonoids -- pharmacology
- Flow Cytometry
- Humans
- Mitogen-Activated Protein Kinases -- metabolism
- Morpholines -- pharmacology
- Piperidines -- pharmacology
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- S Phase
- Signal Transduction
- Time Factors
- Transfection
- Trastuzumab
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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