Local expression of C-type natriuretic peptide suppresses inflammation, eliminates shear stress-induced thrombosis, and prevents neointima formation through enhanced nitric oxide production in rabbit injured carotid arteries. [electronic resource]
Producer: 20021209Description: 1063-9 p. digitalISSN:- 1524-4571
- Adenoviridae -- genetics
- Animals
- Blood Flow Velocity -- drug effects
- Carotid Arteries -- drug effects
- Carotid Artery Thrombosis -- pathology
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Genes, Reporter
- Genetic Therapy
- Genetic Vectors -- administration & dosage
- Humans
- Inflammation -- metabolism
- Intercellular Adhesion Molecule-1 -- biosynthesis
- Lipoproteins -- biosynthesis
- Macrophages -- pathology
- Male
- Natriuretic Peptide, C-Type -- biosynthesis
- Nitric Oxide -- biosynthesis
- Rabbits
- Rats
- Rats, Wistar
- Stress, Mechanical
- Tunica Intima -- drug effects
- Vascular Cell Adhesion Molecule-1 -- biosynthesis
- Vasoconstrictor Agents -- pharmacology
- beta-Galactosidase -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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