Vitamin D and its analog EB1089 induce p27 accumulation and diminish association of p27 with Skp2 independent of PTEN in pituitary corticotroph cells. [electronic resource]
Producer: 20030212Description: 412-9 p. digitalISSN:- 1015-6305
- Adenoma -- drug therapy
- Adrenocorticotropic Hormone -- metabolism
- Animals
- CDC2-CDC28 Kinases
- Calcitriol -- analogs & derivatives
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- agonists
- Cells, Cultured
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Cysteine Endopeptidases -- drug effects
- Humans
- Multienzyme Complexes -- drug effects
- PTEN Phosphohydrolase
- Phosphoric Monoester Hydrolases -- metabolism
- Pituitary Neoplasms -- drug therapy
- Proteasome Endopeptidase Complex
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- S-Phase Kinase-Associated Proteins
- Tumor Suppressor Proteins -- agonists
- Up-Regulation -- drug effects
- Vitamin D -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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