Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. [electronic resource]
Producer: 20030421Description: 1053-62 p. digitalISSN:- 0006-4971
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Division -- drug effects
- Curcumin -- pharmacology
- Down-Regulation -- drug effects
- Drug Synergism
- G1 Phase -- drug effects
- Humans
- I-kappa B Kinase
- Multiple Myeloma -- drug therapy
- NF-kappa B -- antagonists & inhibitors
- Phosphorylation -- drug effects
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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