Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. [electronic resource]
Producer: 20021028Description: 12351-6 p. digitalISSN:- 0027-8424
- Animals
- Cell Line
- Endotoxemia -- complications
- Enzyme Activation -- drug effects
- HMGB1 Protein -- metabolism
- Lipopolysaccharides -- toxicity
- Macrophages -- drug effects
- Male
- Mice
- Mice, Inbred BALB C
- Mitogen-Activated Protein Kinases -- metabolism
- NF-kappa B -- genetics
- Pyruvates -- administration & dosage
- RNA, Messenger -- genetics
- Sepsis -- complications
- Signal Transduction -- drug effects
- Systemic Inflammatory Response Syndrome -- drug therapy
- Tumor Necrosis Factor-alpha -- genetics
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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