Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. [electronic resource]
Producer: 20020924Description: 489-500 p. digitalISSN:- 0092-8674
- CCAAT-Enhancer-Binding Proteins -- metabolism
- Cell Membrane -- metabolism
- Cells, Cultured
- Cholesterol -- biosynthesis
- DNA-Binding Proteins -- metabolism
- Endoplasmic Reticulum -- metabolism
- Eukaryotic Cells -- cytology
- Gene Expression Regulation -- physiology
- Genetic Vectors -- physiology
- Golgi Apparatus -- metabolism
- Homeostasis -- genetics
- Humans
- Intracellular Signaling Peptides and Proteins
- Membrane Proteins -- genetics
- Mutation -- genetics
- Peptide Hydrolases -- metabolism
- Protein Binding -- physiology
- Protein Structure, Tertiary -- physiology
- Protein Transport -- physiology
- Proteins -- genetics
- Sterol Regulatory Element Binding Protein 1
- Sterols -- metabolism
- Transcription Factors
- Transfection
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.