Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeutics. [electronic resource]
Producer: 20020917Description: 501-10 p. digitalISSN:- 0022-1899
- Animals
- Bacterial Proteins
- CD4 Antigens -- genetics
- Cytokines -- blood
- Disease Models, Animal
- Exotoxins -- genetics
- HLA-DQ Antigens -- genetics
- Humans
- Liver -- enzymology
- Membrane Proteins
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic
- Receptors, Antigen, T-Cell, alpha-beta -- metabolism
- Shock, Septic -- etiology
- Streptococcal Infections -- etiology
- Streptococcal Vaccines -- administration & dosage
- Streptococcus pyogenes -- immunology
- Superantigens -- immunology
- T-Lymphocytes -- immunology
- Transgenes
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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