Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeutics.
Welcher, Brent C
Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeutics. [electronic resource] - The Journal of infectious diseases Aug 2002 - 501-10 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-1899
10.1086/341828 doi
Animals
Bacterial Proteins
CD4 Antigens--genetics
Cytokines--blood
Disease Models, Animal
Exotoxins--genetics
HLA-DQ Antigens--genetics
Humans
Liver--enzymology
Membrane Proteins
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Transgenic
Receptors, Antigen, T-Cell, alpha-beta--metabolism
Shock, Septic--etiology
Streptococcal Infections--etiology
Streptococcal Vaccines--administration & dosage
Streptococcus pyogenes--immunology
Superantigens--immunology
T-Lymphocytes--immunology
Transgenes
Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeutics. [electronic resource] - The Journal of infectious diseases Aug 2002 - 501-10 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-1899
10.1086/341828 doi
Animals
Bacterial Proteins
CD4 Antigens--genetics
Cytokines--blood
Disease Models, Animal
Exotoxins--genetics
HLA-DQ Antigens--genetics
Humans
Liver--enzymology
Membrane Proteins
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Transgenic
Receptors, Antigen, T-Cell, alpha-beta--metabolism
Shock, Septic--etiology
Streptococcal Infections--etiology
Streptococcal Vaccines--administration & dosage
Streptococcus pyogenes--immunology
Superantigens--immunology
T-Lymphocytes--immunology
Transgenes