Kit signaling inhibits the sphingomyelin-ceramide pathway through PLC gamma 1: implication in stem cell factor radioprotective effect. [electronic resource]
Producer: 20020912Description: 1294-301 p. digitalISSN:- 0006-4971
- Animals
- Apoptosis -- radiation effects
- B-Lymphocytes -- metabolism
- Cell Death -- radiation effects
- Cell Line
- Ceramides -- metabolism
- Cobalt Radioisotopes
- DNA Repair -- drug effects
- Enzyme Inhibitors -- pharmacology
- Estrenes -- pharmacology
- Gene Expression
- Humans
- Indoles
- Isoenzymes -- antagonists & inhibitors
- Kinetics
- Mice
- Microscopy, Fluorescence
- Phosphatidylinositol 3-Kinases -- metabolism
- Phospholipase C gamma
- Proto-Oncogene Proteins c-kit -- genetics
- Pyrrolidinones -- pharmacology
- Radiation-Protective Agents
- Signal Transduction
- Sphingomyelin Phosphodiesterase -- metabolism
- Sphingomyelins -- metabolism
- Stem Cell Factor -- pharmacology
- Transfection
- Type C Phospholipases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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