Kit signaling inhibits the sphingomyelin-ceramide pathway through PLC gamma 1: implication in stem cell factor radioprotective effect.

Maddens, Stéphane

Kit signaling inhibits the sphingomyelin-ceramide pathway through PLC gamma 1: implication in stem cell factor radioprotective effect. [electronic resource] - Blood Aug 2002 - 1294-301 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971


Animals
Apoptosis--radiation effects
B-Lymphocytes--metabolism
Cell Death--radiation effects
Cell Line
Ceramides--metabolism
Cobalt Radioisotopes
DNA Repair--drug effects
Enzyme Inhibitors--pharmacology
Estrenes--pharmacology
Gene Expression
Humans
Indoles
Isoenzymes--antagonists & inhibitors
Kinetics
Mice
Microscopy, Fluorescence
Phosphatidylinositol 3-Kinases--metabolism
Phospholipase C gamma
Proto-Oncogene Proteins c-kit--genetics
Pyrrolidinones--pharmacology
Radiation-Protective Agents
Signal Transduction
Sphingomyelin Phosphodiesterase--metabolism
Sphingomyelins--metabolism
Stem Cell Factor--pharmacology
Transfection
Type C Phospholipases--antagonists & inhibitors