Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase. [electronic resource]
Producer: 20020828Description: 1028-36 p. digitalISSN:- 0022-1767
- Administration, Inhalation
- Aerosols
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- administration & dosage
- Bronchoalveolar Lavage Fluid -- cytology
- Cell Adhesion Molecules -- biosynthesis
- Drug Administration Schedule
- Enzyme Inhibitors -- administration & dosage
- Enzyme Precursors -- antagonists & inhibitors
- In Vitro Techniques
- Inflammation -- enzymology
- Intracellular Signaling Peptides and Proteins
- Leukocyte Count
- Lung -- drug effects
- Male
- Muscle Contraction -- drug effects
- Oligodeoxyribonucleotides, Antisense -- administration & dosage
- Ovalbumin -- administration & dosage
- Perfusion
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Rats
- Rats, Inbred BN
- Rats, Sprague-Dawley
- Respiratory Hypersensitivity -- enzymology
- Syk Kinase
- Time Factors
- Trachea -- drug effects
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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