Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase.
Stenton, Grant R
Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Jul 2002 - 1028-36 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-1767
10.4049/jimmunol.169.2.1028 doi
Administration, Inhalation
Aerosols
Animals
Anti-Inflammatory Agents, Non-Steroidal--administration & dosage
Bronchoalveolar Lavage Fluid--cytology
Cell Adhesion Molecules--biosynthesis
Drug Administration Schedule
Enzyme Inhibitors--administration & dosage
Enzyme Precursors--antagonists & inhibitors
In Vitro Techniques
Inflammation--enzymology
Intracellular Signaling Peptides and Proteins
Leukocyte Count
Lung--drug effects
Male
Muscle Contraction--drug effects
Oligodeoxyribonucleotides, Antisense--administration & dosage
Ovalbumin--administration & dosage
Perfusion
Protein-Tyrosine Kinases--antagonists & inhibitors
Rats
Rats, Inbred BN
Rats, Sprague-Dawley
Respiratory Hypersensitivity--enzymology
Syk Kinase
Time Factors
Trachea--drug effects
Tumor Necrosis Factor-alpha--antagonists & inhibitors
Up-Regulation--drug effects
Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Jul 2002 - 1028-36 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-1767
10.4049/jimmunol.169.2.1028 doi
Administration, Inhalation
Aerosols
Animals
Anti-Inflammatory Agents, Non-Steroidal--administration & dosage
Bronchoalveolar Lavage Fluid--cytology
Cell Adhesion Molecules--biosynthesis
Drug Administration Schedule
Enzyme Inhibitors--administration & dosage
Enzyme Precursors--antagonists & inhibitors
In Vitro Techniques
Inflammation--enzymology
Intracellular Signaling Peptides and Proteins
Leukocyte Count
Lung--drug effects
Male
Muscle Contraction--drug effects
Oligodeoxyribonucleotides, Antisense--administration & dosage
Ovalbumin--administration & dosage
Perfusion
Protein-Tyrosine Kinases--antagonists & inhibitors
Rats
Rats, Inbred BN
Rats, Sprague-Dawley
Respiratory Hypersensitivity--enzymology
Syk Kinase
Time Factors
Trachea--drug effects
Tumor Necrosis Factor-alpha--antagonists & inhibitors
Up-Regulation--drug effects