Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1. [electronic resource]
Producer: 20020802Description: 1125-37 p. digitalISSN:- 0021-9525
- Anaphase -- physiology
- Biomarkers
- Cell Cycle Proteins -- genetics
- Cell Line
- Chromatids -- physiology
- Cyclin B -- metabolism
- Cyclin B1
- Cyclin-Dependent Kinases -- metabolism
- HeLa Cells
- Humans
- Hydrolysis
- Kinetics
- Metaphase -- physiology
- Mutation
- Neoplasm Proteins -- metabolism
- Phenotype
- Recombinant Fusion Proteins -- metabolism
- Securin
- Sequence Deletion
- Spindle Apparatus -- physiology
- Transcriptional Activation
- Tumor Cells, Cultured
- Ubiquitins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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