Importance of specific hydrogen-bond donor-acceptor interactions for the key carbocycle-forming reaction catalyzed by 2-deoxy-scyllo-inosose synthase in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics. [electronic resource]
Producer: 20021018Description: 3979-84 p. digitalISSN:- 0022-3263
- Aminoglycosides
- Anti-Bacterial Agents -- biosynthesis
- Bacillus -- enzymology
- Catalysis
- Chromatography, High Pressure Liquid
- Cyclization
- Escherichia coli -- enzymology
- Glucose-6-Phosphate -- analogs & derivatives
- Hexosamines -- biosynthesis
- Hydrogen Bonding
- Hydrogen-Ion Concentration
- Inositol -- analogs & derivatives
- Kinetics
- Lyases -- metabolism
- Magnetic Resonance Spectroscopy
- Models, Molecular
- Molecular Structure
- Oxidation-Reduction
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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