Importance of specific hydrogen-bond donor-acceptor interactions for the key carbocycle-forming reaction catalyzed by 2-deoxy-scyllo-inosose synthase in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics.
Eguchi, Tadashi
Importance of specific hydrogen-bond donor-acceptor interactions for the key carbocycle-forming reaction catalyzed by 2-deoxy-scyllo-inosose synthase in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics. [electronic resource] - The Journal of organic chemistry Jun 2002 - 3979-84 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3263
10.1021/jo011107n doi
Aminoglycosides
Anti-Bacterial Agents--biosynthesis
Bacillus--enzymology
Catalysis
Chromatography, High Pressure Liquid
Cyclization
Escherichia coli--enzymology
Glucose-6-Phosphate--analogs & derivatives
Hexosamines--biosynthesis
Hydrogen Bonding
Hydrogen-Ion Concentration
Inositol--analogs & derivatives
Kinetics
Lyases--metabolism
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Structure
Oxidation-Reduction
Substrate Specificity
Importance of specific hydrogen-bond donor-acceptor interactions for the key carbocycle-forming reaction catalyzed by 2-deoxy-scyllo-inosose synthase in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics. [electronic resource] - The Journal of organic chemistry Jun 2002 - 3979-84 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3263
10.1021/jo011107n doi
Aminoglycosides
Anti-Bacterial Agents--biosynthesis
Bacillus--enzymology
Catalysis
Chromatography, High Pressure Liquid
Cyclization
Escherichia coli--enzymology
Glucose-6-Phosphate--analogs & derivatives
Hexosamines--biosynthesis
Hydrogen Bonding
Hydrogen-Ion Concentration
Inositol--analogs & derivatives
Kinetics
Lyases--metabolism
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Structure
Oxidation-Reduction
Substrate Specificity