Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine. [electronic resource]
Producer: 20020531Description: 2414-22 p. digitalISSN:- 0008-5472
- 3T3 Cells
- Amino Acid Substitution
- Animals
- Catalysis
- Cell Transformation, Neoplastic
- Drosophila Proteins
- Humans
- Mice
- Multiple Endocrine Neoplasia Type 2a -- genetics
- Mutagenesis
- Phenylalanine -- genetics
- Phosphorylation
- Phosphotyrosine -- metabolism
- Polymerase Chain Reaction
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-ret
- Receptor Protein-Tyrosine Kinases -- genetics
- Transfection
- Tyrosine -- genetics
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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