Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.

Kato, Masashi

Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine. [electronic resource] - Cancer research Apr 2002 - 2414-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


3T3 Cells
Amino Acid Substitution
Animals
Catalysis
Cell Transformation, Neoplastic
Drosophila Proteins
Humans
Mice
Multiple Endocrine Neoplasia Type 2a--genetics
Mutagenesis
Phenylalanine--genetics
Phosphorylation
Phosphotyrosine--metabolism
Polymerase Chain Reaction
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases--genetics
Transfection
Tyrosine--genetics
src-Family Kinases--metabolism