Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. [electronic resource]
Producer: 20020403Description: 2318-28 p. digitalISSN:- 0270-7306
- Animals
- Blotting, Western
- Body Patterning -- genetics
- Cell Cycle Proteins
- Congenital Abnormalities -- genetics
- Embryo Loss -- genetics
- Embryonic and Fetal Development -- genetics
- Gastrula -- metabolism
- Gene Deletion
- Genes, Essential -- genetics
- Histone Chaperones
- Homozygote
- Immunohistochemistry
- In Situ Hybridization
- Mesoderm -- metabolism
- Mice
- Mutagenesis, Site-Directed -- genetics
- Nervous System -- embryology
- Nuclear Proteins -- deficiency
- Phenotype
- RNA, Messenger -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Transcription Factors -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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