Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality.

Roberts, Catherine

Targeted mutagenesis of the Hira gene results in gastrulation defects and patterning abnormalities of mesoendodermal derivatives prior to early embryonic lethality. [electronic resource] - Molecular and cellular biology Apr 2002 - 2318-28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0270-7306

10.1128/MCB.22.7.2318-2328.2002 doi


Animals
Blotting, Western
Body Patterning--genetics
Cell Cycle Proteins
Congenital Abnormalities--genetics
Embryo Loss--genetics
Embryonic and Fetal Development--genetics
Gastrula--metabolism
Gene Deletion
Genes, Essential--genetics
Histone Chaperones
Homozygote
Immunohistochemistry
In Situ Hybridization
Mesoderm--metabolism
Mice
Mutagenesis, Site-Directed--genetics
Nervous System--embryology
Nuclear Proteins--deficiency
Phenotype
RNA, Messenger--genetics
Reverse Transcriptase Polymerase Chain Reaction
Transcription Factors--deficiency