Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity. [electronic resource]
Producer: 20020329Description: 605-11 p. digitalISSN:- 0007-0920
- Animals
- Antineoplastic Agents -- pharmacology
- Benzothiazoles
- Breast Neoplasms -- metabolism
- Cell Division -- drug effects
- Chromatography, High Pressure Liquid
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- genetics
- Dose-Response Relationship, Drug
- Female
- Humans
- Imidazoles -- pharmacology
- Mammary Neoplasms, Experimental -- metabolism
- Mice
- Mice, Inbred Strains
- Mixed Function Oxygenases -- antagonists & inhibitors
- Retinoic Acid 4-Hydroxylase
- Reverse Transcriptase Polymerase Chain Reaction
- Thiazoles -- pharmacology
- Tretinoin -- metabolism
- Tumor Cells, Cultured -- drug effects
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Publication Type: Comparative Study; Journal Article
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