Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension. [electronic resource]
Producer: 20020212Description: 516-21 p. digitalISSN:- 1524-4539
- Actins -- analysis
- Animals
- Elastin -- metabolism
- Endothelin-1 -- biosynthesis
- Hematocrit
- Hypertension, Pulmonary -- etiology
- Hypertrophy, Right Ventricular -- etiology
- Hypoxia -- complications
- Kinetics
- Matrix Metalloproteinases -- metabolism
- Mice
- Mice, Transgenic
- Pressure
- Proteinase Inhibitory Proteins, Secretory
- Proteins -- genetics
- Pulmonary Artery -- pathology
- RNA, Messenger -- biosynthesis
- Serine Proteinase Inhibitors -- genetics
- Up-Regulation
- Ventricular Pressure
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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