Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension.

Zaidi, Syed H E

Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension. [electronic resource] - Circulation Jan 2002 - 516-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4539

10.1161/hc0402.102866 doi


Actins--analysis
Animals
Elastin--metabolism
Endothelin-1--biosynthesis
Hematocrit
Hypertension, Pulmonary--etiology
Hypertrophy, Right Ventricular--etiology
Hypoxia--complications
Kinetics
Matrix Metalloproteinases--metabolism
Mice
Mice, Transgenic
Pressure
Proteinase Inhibitory Proteins, Secretory
Proteins--genetics
Pulmonary Artery--pathology
RNA, Messenger--biosynthesis
Serine Proteinase Inhibitors--genetics
Up-Regulation
Ventricular Pressure