Nerve growth factor-induced p75-mediated death of cultured hippocampal neurons is age-dependent and transduced through ceramide generated by neutral sphingomyelinase. [electronic resource]
Producer: 20020429Description: 9812-8 p. digitalISSN:- 0021-9258
- Age Factors
- Amides -- metabolism
- Animals
- Axons -- metabolism
- Blotting, Western
- Cell Death
- Cells, Cultured
- Ceramides -- metabolism
- Dose-Response Relationship, Drug
- Hippocampus -- cytology
- Mice
- Mice, Inbred C57BL
- Mitogen-Activated Protein Kinase 8
- Mitogen-Activated Protein Kinases -- metabolism
- Nerve Growth Factor -- metabolism
- Neurons -- metabolism
- Phosphorylation
- Pyrones -- metabolism
- Rats
- Rats, Wistar
- Receptor, Nerve Growth Factor
- Receptors, Nerve Growth Factor -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Sphingomyelin Phosphodiesterase -- metabolism
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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