Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. [electronic resource]
Producer: 20020617Description: 359-70 p. digitalISSN:- 1084-9785
- Adenocarcinoma -- blood supply
- Angiogenesis Inhibitors -- administration & dosage
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- Apoptosis -- drug effects
- Deoxycytidine -- administration & dosage
- Enzyme Inhibitors -- administration & dosage
- Humans
- In Situ Nick-End Labeling
- Male
- Mice
- Mice, Nude
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Neoplasm Proteins -- analysis
- Neoplasm Transplantation
- Pancreatic Neoplasms -- blood supply
- Phthalazines -- administration & dosage
- Platelet Endothelial Cell Adhesion Molecule-1 -- analysis
- Proliferating Cell Nuclear Antigen -- analysis
- Pyridines
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Receptors, Growth Factor -- antagonists & inhibitors
- Receptors, Vascular Endothelial Growth Factor
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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