The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0. [electronic resource]
Producer: 20020212Description: 1077-88 p. digitalISSN:- 0022-538X
- Animals
- Cell Nucleus -- metabolism
- Chlorocebus aethiops
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Electrophoresis, Polyacrylamide Gel
- Enzyme Inhibitors -- pharmacology
- Gene Expression
- Genetic Engineering
- Herpesvirus 1, Human -- drug effects
- Humans
- Immediate-Early Proteins -- drug effects
- Peptide Mapping
- Phosphoproteins -- analysis
- Phosphorylation -- drug effects
- Promoter Regions, Genetic
- Protein Processing, Post-Translational -- drug effects
- Purines -- pharmacology
- Roscovitine
- Trans-Activators -- drug effects
- Transcriptional Activation -- drug effects
- Trypsin
- Ubiquitin-Protein Ligases
- Vero Cells
- Viral Proteins -- genetics
- beta-Galactosidase -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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