Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality. [electronic resource]
Producer: 20020122Description: 1-18 p. digitalISSN:- 0022-2623
- Antiviral Agents -- chemical synthesis
- Binding Sites
- Crystallography, X-Ray
- Cytomegalovirus -- chemistry
- Lactams -- chemical synthesis
- Mass Spectrometry
- Models, Molecular
- Protease Inhibitors -- chemical synthesis
- Pyrroles -- chemical synthesis
- Serine Endopeptidases -- chemistry
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article
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