Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality. (Record no. 11666992)

MARC details
000 -LEADER
fixed length control field 01656 a2200457 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250514020926.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200201s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0022-2623
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1021/jm0102203
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Borthwick, Alan D
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20020122
245 00 - TITLE STATEMENT
Title Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Journal of medicinal chemistry
Date of publication, distribution, etc. Jan 2002
300 ## - PHYSICAL DESCRIPTION
Extent 1-18 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Antiviral Agents
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Binding Sites
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Crystallography, X-Ray
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cytomegalovirus
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Lactams
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mass Spectrometry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Molecular
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protease Inhibitors
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pyrroles
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Serine Endopeptidases
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Stereoisomerism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Structure-Activity Relationship
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Crame, Andrew J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ertl, Peter F
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Exall, Anne M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Haley, Terry M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hart, Graham J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mason, Andrew M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pennell, Andrew M K
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Singh, Onkar M P
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Weingarten, Gordon G
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Woolven, James M
773 0# - HOST ITEM ENTRY
Title Journal of medicinal chemistry
Related parts vol. 45
-- no. 1
-- p. 1-18
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1021/jm0102203">https://doi.org/10.1021/jm0102203</a>
Public note Available from publisher's website

No items available.