Induction of G(2)/M phase arrest and apoptosis by a new synthetic anti-cancer agent, DW2282, in promyelocytic leukemia (HL-60) cells. [electronic resource]
Producer: 20020102Description: 1439-47 p. digitalISSN:- 0006-2952
- Antineoplastic Agents -- pharmacology
- Apoptosis
- CDC2 Protein Kinase -- metabolism
- Caspase 3
- Caspases -- metabolism
- Cell Division -- drug effects
- Down-Regulation -- drug effects
- Enzyme Activation -- drug effects
- G2 Phase -- drug effects
- HL-60 Cells
- Humans
- Imidazoles -- pharmacology
- Leukemia, Promyelocytic, Acute
- Mitosis -- drug effects
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerases
- Proteins -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- Sulfones -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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