Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation. [electronic resource]
Producer: 20011212Description: 8290-7 p. digitalISSN:- 0008-5472
- Adaptor Proteins, Signal Transducing
- Base Pair Mismatch
- CDC2 Protein Kinase -- metabolism
- Carrier Proteins
- Cell Survival -- drug effects
- Colorectal Neoplasms -- metabolism
- DNA Repair -- physiology
- Endometrial Neoplasms -- metabolism
- Female
- G2 Phase -- drug effects
- Humans
- MutL Protein Homolog 1
- Neoplasm Proteins -- deficiency
- Nuclear Proteins
- Ovarian Neoplasms -- metabolism
- Phosphorylation
- S Phase -- drug effects
- Signal Transduction -- physiology
- Thioguanine -- pharmacology
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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