Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.

Yan, T

Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation. [electronic resource] - Cancer research Nov 2001 - 8290-7 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0008-5472


Adaptor Proteins, Signal Transducing
Base Pair Mismatch
CDC2 Protein Kinase--metabolism
Carrier Proteins
Cell Survival--drug effects
Colorectal Neoplasms--metabolism
DNA Repair--physiology
Endometrial Neoplasms--metabolism
Female
G2 Phase--drug effects
Humans
MutL Protein Homolog 1
Neoplasm Proteins--deficiency
Nuclear Proteins
Ovarian Neoplasms--metabolism
Phosphorylation
S Phase--drug effects
Signal Transduction--physiology
Thioguanine--pharmacology
Tumor Cells, Cultured