A Phase I clinical and pharmacological evaluation of sodium phenylbutyrate on an 120-h infusion schedule. [electronic resource]
Producer: 20011205Description: 3047-55 p. digitalISSN:- 1078-0432
- Adult
- Antineoplastic Agents -- adverse effects
- Chromatography, High Pressure Liquid
- Disorders of Excessive Somnolence -- chemically induced
- Dose-Response Relationship, Drug
- Fatigue -- chemically induced
- Female
- Glutamine -- analogs & derivatives
- Humans
- Hypokalemia -- chemically induced
- Infusions, Intravenous
- Male
- Metabolic Clearance Rate
- Nausea -- chemically induced
- Neoplasms -- drug therapy
- Neutropenia -- chemically induced
- Patient Dropouts
- Phenylacetates -- blood
- Phenylbutyrates -- adverse effects
- Prostate-Specific Antigen -- blood
- Prostatic Neoplasms -- blood
- Time Factors
- Tumor Cells, Cultured
- Uric Acid -- blood
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Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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