IL-6 deficiency allows for enhanced therapeutic value after bone marrow transplantation across a minor histocompatibility barrier in the twitcher (globoid cell leukodystrophy) mouse. [electronic resource]
Producer: 20010913Description: 298-307 p. digitalISSN:- 0360-4012
- Animals
- Astrocytes -- pathology
- Blood-Brain Barrier
- Body Weight
- Bone Marrow Transplantation -- immunology
- Brain -- blood supply
- Demyelinating Diseases -- immunology
- Female
- Gliosis -- pathology
- Graft vs Host Disease -- genetics
- Immunohistochemistry
- Interleukin-6 -- genetics
- Lectins
- Leukodystrophy, Globoid Cell -- immunology
- Macrophages -- pathology
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, Neurologic Mutants
- Minor Histocompatibility Antigens -- immunology
- Myelin Basic Protein -- analysis
- Serum Albumin -- analysis
- Survival Rate
- beta-Galactosidase -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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