IL-6 deficiency allows for enhanced therapeutic value after bone marrow transplantation across a minor histocompatibility barrier in the twitcher (globoid cell leukodystrophy) mouse.

Biswas, S

IL-6 deficiency allows for enhanced therapeutic value after bone marrow transplantation across a minor histocompatibility barrier in the twitcher (globoid cell leukodystrophy) mouse. [electronic resource] - Journal of neuroscience research Aug 2001 - 298-307 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0360-4012

10.1002/jnr.1154 doi


Animals
Astrocytes--pathology
Blood-Brain Barrier
Body Weight
Bone Marrow Transplantation--immunology
Brain--blood supply
Demyelinating Diseases--immunology
Female
Gliosis--pathology
Graft vs Host Disease--genetics
Immunohistochemistry
Interleukin-6--genetics
Lectins
Leukodystrophy, Globoid Cell--immunology
Macrophages--pathology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Neurologic Mutants
Minor Histocompatibility Antigens--immunology
Myelin Basic Protein--analysis
Serum Albumin--analysis
Survival Rate
beta-Galactosidase--genetics